George Zimmerman sues NBC and reporters

ORLANDO, Fla. (AP) — George Zimmerman sued NBC on Thursday, claiming he was defamed when the network edited his 911 call to police after the shooting of Trayvon Martin to make it sound like he was racist.

The former neighborhood watch volunteer filed the lawsuit seeking an undisclosed amount of money in Seminole County, outside Orlando. Also named in the complaint were three reporters covering the story for NBC or an NBC-owned television station.

The complaint said the airing of the edited call has inflicted emotional distress on Zimmerman, making him fear for his life and causing him to suffer nausea, insomnia and anxiety.

The lawsuit claims NBC edited his phone call to a dispatcher in February. In the call, Zimmerman describes following Martin in the gated community where he lived, just moments before he fatally shot the 17-year-old teen during a confrontation.

“NBC saw the death of Trayvon Martin not as a tragedy but as an opportunity to increase ratings, and so set about to create a myth that George Zimmerman was a racist and predatory villain,” the lawsuit claims.

NBC spokeswoman Kathy Kelly-Brown said the network strongly disagreed with the accusations made in the complaint.

“There was no intent to portray Mr. Zimmerman unfairly,” she said. “We intend to vigorously defend our position in court.”

Three employees of the network or its Miami affiliate lost their jobs because of the changes.

Zimmerman is charged with second-degree murder but has pleaded not guilty, claiming self-defense under Florida’s “stand your ground law.”

The call viewers heard was trimmed to suggest that Zimmerman volunteered to police, with no prompting, that Martin was black: “This guy looks like he’s up to no good. He looks black.”

But the portion of the tape that was deleted had the 911 dispatcher asking Zimmerman if the person who had raised his suspicion was “black, white or Hispanic,” to which Zimmerman responded, “He looks black.”

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Celebrations planned as Wash. legalizes marijuana

SEATTLE (AP) — Legal marijuana possession becomes a reality under Washington state law on Thursday, and some people planned to celebrate the new law by breaking it.

Voters in Washington and Colorado last month made those the first states to decriminalize and regulate the recreational use of marijuana. Washington's law takes effect Thursday and allows adults to have up to an ounce of pot — but it bans public use of marijuana, which is punishable by a fine, just like drinking in public.

Nevertheless, some people planned to gather at 12:01 a.m. PST Thursday to smoke in public beneath Seattle's Space Needle. Others planned a midnight party outside the Seattle headquarters of Hempfest, the 21-year-old festival that attracts tens of thousands of pot fans every summer.

"This is a big day because all our lives we've been living under the iron curtain of prohibition," said Hempfest director Vivian McPeak. "The whole world sees that prohibition just took a body blow."

In another sweeping change for Washington, Gov. Chris Gregoire on Wednesday signed into law a measure that legalizes same-sex marriage. The state joins several others that allow gay and lesbian couples to wed.

That law also takes effect Thursday, when gay and lesbian couples can start picking up their wedding certificates and licenses at county auditors' offices. Those offices in King County, the state's largest and home to Seattle, and Thurston County, home to the state capital of Olympia, planned to open the earliest, at 12:01 a.m. Thursday, to start issuing marriage licenses. Because the state has a three-day waiting period, the earliest that weddings can take place is Sunday.

The Seattle Police Department provided this public marijuana use enforcement guidance to its officers via email Wednesday night: "Until further notice, officers shall not take any enforcement action — other than to issue a verbal warning — for a violation of Initiative 502."

Thanks to a 2003 law, marijuana enforcement remains the department's lowest priority. Even before I-502 passed on Nov. 6, police rarely busted people at Hempfest, despite widespread pot use, and the city attorney here doesn't prosecute people for having small amounts of marijuana.

Officers will be advising people to take their weed inside, police spokesman Jonah Spangenthal-Lee wrote on the SPD Blotter. "The police department believes that, under state law, you may responsibly get baked, order some pizzas and enjoy a 'Lord of the Rings' marathon in the privacy of your own home, if you want to."

Washington's new law decriminalizes possession of up to an ounce for those over 21, but for now selling marijuana remains illegal. I-502 gives the state a year to come up with a system of state-licensed growers, processors and retail stores, with the marijuana taxed 25 percent at each stage. Analysts have estimated that a legal pot market could bring Washington hundreds of millions of dollars a year in new tax revenue for schools, health care and basic government functions.

But marijuana remains illegal under federal law. That means federal agents can still arrest people for it, and it's banned from federal properties, including military bases and national parks.

The Justice Department has not said whether it will sue to try to block the regulatory schemes in Washington and Colorado from taking effect.

"The department's responsibility to enforce the Controlled Substances Act remains unchanged," said a statement issued Wednesday by the Seattle U.S. attorney's office. "Neither states nor the executive branch can nullify a statute passed by Congress" — a non-issue, since the measures passed in Washington and Colorado don't "nullify" federal law, which federal agents remain free to enforce.

The legal question is whether the establishment of a regulated marijuana market would "frustrate the purpose" of the federal pot prohibition, and many constitutional law scholars say it very likely would.

That leaves the political question of whether the administration wants to try to block the regulatory system, even though it would remain legal to possess up to an ounce of marijuana.

Colorado's measure, as far as decriminalizing possession goes, is set to take effect by Jan. 5. That state's regulatory scheme is due to be up and running by October 2013.

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Johnson can be reached at https://twitter.com/GeneAPseattle

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George Zimmerman sues NBC and reporters

ORLANDO, Fla. (AP) — George Zimmerman sued NBC on Thursday, claiming he was defamed when the network edited his 911 call to police after the shooting of Trayvon Martin to make it sound like he was racist.

The former neighborhood watch volunteer filed the lawsuit seeking an undisclosed amount of money in Seminole County, outside Orlando. Also named in the complaint were three reporters covering the story for NBC or an NBC-owned television station.

The complaint said the airing of the edited call has inflicted emotional distress on Zimmerman, making him fear for his life and causing him to suffer nausea, insomnia and anxiety.

The lawsuit claims NBC edited his phone call to a dispatcher in February. In the call, Zimmerman describes following Martin in the gated community where he lived, just moments before he fatally shot the 17-year-old teen during a confrontation.

"NBC saw the death of Trayvon Martin not as a tragedy but as an opportunity to increase ratings, and so set about to create a myth that George Zimmerman was a racist and predatory villain," the lawsuit claims.

NBC spokeswoman Kathy Kelly-Brown said the network strongly disagreed with the accusations made in the complaint.

"There was no intent to portray Mr. Zimmerman unfairly," she said. "We intend to vigorously defend our position in court."

Three employees of the network or its Miami affiliate lost their jobs because of the changes.

Zimmerman is charged with second-degree murder but has pleaded not guilty, claiming self-defense under Florida's "stand your ground law."

The call viewers heard was trimmed to suggest that Zimmerman volunteered to police, with no prompting, that Martin was black: "This guy looks like he's up to no good. He looks black."

But the portion of the tape that was deleted had the 911 dispatcher asking Zimmerman if the person who had raised his suspicion was "black, white or Hispanic," to which Zimmerman responded, "He looks black."

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Lurie Children's Hospital sees surge in patients at new Chicago building

Executives at the Ann & Robert H. Lurie Children's Hospital of Chicago expected a "bump" in patients when the $855 million hospital opened in June.

They weren't prepared for a mountain.

Since the former Children's Memorial traded its patchwork of aging buildings in Lincoln Park for a new high-rise in Streeterville on June 9, patient volume has surged, more than doubling hospital projections.

The number of patients is up about 16 percent in the first five months, according to hospital data, an increase driven by an influx of children with more acute health problems, including transplant patients, kids with heart problems and others in need of specialized care.

Revenue over that five-month period increased 12.9 percent to $222 million.

"We expected to have a new-hospital bump in (patients). We had a new-hospital mountain," said Michelle Stephenson, Lurie Children's chief patient care services officer and chief nurse executive. "We've had some months where the (number of inpatients) was 24 percent over what we expected. "

To meet the demand, the hospital hired 151 nurses to ensure full coverage, she said.

Those new hires came on top of about three dozen pediatric specialists and department heads Lurie Children's recruited in the run-up to the hospital opening.

Stephenson said the hospital has yet to determine the specific reasons behind the jump in patients, but said data shows it is drawing more children from the collar counties and downstate.

She also cited the location, adjacent to Northwestern Memorial Hospital, Northwestern University's Feinberg School of Medicine and Prentice Women's Hospital, which is connected to Lurie via an enclosed skyway.

Moving 31/2 miles south next to Prentice, which sends Lurie about a quarter of its patients, is likely a significant factor in the patient boom, said Jay Warden, a senior vice president at The Camden Group, a consulting firm.

"It used to be a challenge for moms to have a baby transferred to Children's while they had to stay at Prentice until they're discharged," Warden said. "Now it's the best of both worlds for both hospitals."

Warden said hospitals typically get a burst of new patients when they open facilities, in part because of the accompanying marketing and publicity blitz. That's not always the case with children's hospitals, which tend to serve the sickest and smallest of patients who have few other options.

He said limitations at the old hospital likely kept some patients away.

Indeed, Children's Memorial had a listed capacity of 247 beds, but with shared rooms and other factors, executives considered the hospital full at 220 patients, Stephenson said. The Lurie hospital has a capacity of 288 beds in all-private rooms, which it has come close to filling on a few occasions.

One ward that's consistently bursting at the seams is the neonatal intensive care unit, which was built to handle 44 patients but is averaging about 50. Some of the children have been bumped into shared space in the hospital's cardiac care unit, Stephenson said.

As for patients, the new facility has been a hit, with satisfaction scores up an average of 10 percent, hospital officials said.

Tina Sneed, whose 18-year-old daughter Whitney Ballard recently underwent a liver transplant at the hospital, said she's happy with the expanded rooms and new areas for parents.

She and her daughter have made several 7-hour trips from Kentucky in the last 18 months to see specialists, including overnight stays at both facilities.

Her only complaint?

"The waiting room was kind of crowded," she said. "It was nothing too bad, they just have so many (surgeries) going on at the same time we barely had room to move in there."

pfrost@tribune.com

Twitter @peterfrost

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Grammy Awards: Frank Ocean, 5 other artists get 6 nominations

Six artists received six nominations each Wednesday for the 55th Grammy Awards. But none was more notable than rising R&B singer Frank Ocean, who earned nods in three of the top four categories.

Ocean was joined by Kanye West, the Black Keys’ Dan Auerbach, fun., Mumford & Sons and Jay-Z with a half-dozen nominations in the nationally televised prelude to the Grammys, which will be awarded Feb. 10. But Ocean’s multitude of nominations may have been the most surprising given the story behind his major-label debut, “Channel Orange,” nominated for album of the year along with the the Black Keys (“El Camino”), fun. (“Some Nights”), Mumford & Sons (“Babel”), and Jack White (“Blunderbuss”).

Among those shunned were big-selling releases by hip-hop star Drake, whose “Take Care” album got nods only in the rap categories; veteran Lionel Richie, who had a major comeback with a country album, “Tuskegee”; Bruce Springsteen, who launched a well-received world tour on the heels of his politically charged “Wrecking Ball” album; and teen-pop sensations One Direction.

Instead the top-award nominees featured a handful of relative newcomers: fun., Mumford & Sons, Gotye, Miguel and Ocean. A member of the notorious Odd Future hip-hop collective, Ocean made waves earlier this year by acknowledging that some songs on the album were inspired by an unrequited love affair with another man. Ocean’s dignified openness made him a hero to the gay and bisexual communities, even as other fans voiced their intolerance. Yet Ocean’s prowess as a songwriter and singer transcended the controversy, and “Channel Orange” was hailed as a soul classic by many critics. It has sold more than 300,000 copies after debuting at No. 2 on the Billboard Top 200.

Ocean was nominated for three of the four major awards: In addition to his album-of-the-year nod, he is in contention for record of the year (“Thinkin’ Bout You”) and best new artist, which included some heavy competition: Alabama Shakes, fun., Hunter Hayes and the Lumineers.

The other nominees for record of the year, which is awarded for a recording’s overall sound and production, include the Black Keys, Kelly Clarkson, fun., Gotye and Taylor Swift. The latter singer was honored for the single “We are Never Ever Getting Back Together,” but her best-selling “Red” album was released after the Sept. 30 deadline for nominations.

Getting nods for song of the year, which is awarded to songwriters, included Ed Sheeran’s “The A Team,” Miguel’s “Adorn,” Carly Rae Jepsen’s “Call Me Maybe,” Kelly Clarkson’s “Stronger (What Doesn’t Kill You),” and fun.’s “We are Young.”

Five-time nominees included rising R&B star Miguel, the Black Keys and 18-time-winner Chick Corea. The rapper Nas, producer-songwriter Jeff Bhasker and recording engineer Bob Ludwig received four nominations apiece.

The nationally televised event was heavy on country performers such as Luke Bryan, the Band Perry, Dierks Bentley and Hunter Hayes, in tribute to its Nashville location. The show's cohosting duties were split between L.L. Cool J and Taylor Swift, who were notable only for their awkwardness, particularly during a "duet" in which the country-pop singer beat-boxed while the rapper "sang."

Among artists with Chicago connections, West led the way with his six nominations, five of which were in rap categories. Also getting nods were R. Kelly for best R&B album (“Write Me Back”), Lupe Fiasco for best rap album (“Food & Liquor II: The Great American Rap Album, Pt. 1”), Kurt Elling for best jazz vocal album (“1619 Broadway: The Brill Building Project") and Shemekia Copeland for best blues album (“33 1/3”). The Chicago contemporary ensemble eighth blackbird received nominations in two categories, best chamber music/small ensemble performance and best classical contemporary composition, for its album "Meanwhile," released on Chicago's Cedille label.  

greg@gregkot.com

Tribune music critics Howard Reich and John Von Rhein contributed to this report.

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Guatemala detains software guru McAfee, to expel him to Belize

GUATEMALA CITY (Reuters) - Guatemalan police arrested U.S. software guru John McAfee on Wednesday for illegally entering the country and said it would expel him to neighboring Belize, which he fled after being sought for questioning over his neighbor's murder.

McAfee, who had been in hiding for three weeks, crossed into Guatemala with his girlfriend, Samantha, to evade authorities in Belize who wanted to question him as "a person of interest" about the killing of fellow American Gregory Faull.

"He entered the country illegally and we are going to seek his expulsion for this crime," Interior Minister Mauricio Lopez Bonilla said.

Guatemala government spokesman Francisco Cuevas said McAfee would be expelled to Belize and he expected the process to be completed by early Thursday morning.

There is no international arrest warrant for McAfee. Police in Belize say he is a person of interest in their murder investigation and is not a prime suspect.

McAfee was taken to a residence belonging to the immigration department guarded by a small group of police.

On Tuesday, McAfee said he would seek political asylum in Guatemala, which has been embroiled in a long-running territorial dispute with Belize. There is no extradition treaty between the two countries, and there is no international arrest warrant out for McAfee.

McAfee says he fears Belizean authorities would kill him if he returned there for questioning. Belize's prime minister has denied the claim, calling the 67-year-old software entrepreneur paranoid and "bonkers."

McAfee has been living in the tiny Central American nation for about four years.

He was one of Silicon Valley's first entrepreneurs to build an Internet fortune. The former Lockheed systems consultant started McAfee Associates in the late 1980s.

McAfee has no relationship now with the company, which has been sold to Intel Corp.

(Additional reporting by Sofia Menchu and Lomi Kriel; Writing by Gabriel Stargardter; Editing by Simon Gardner and Philip Barbara)

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Bryant eclipses 30,000, Lakers beat Hornets 103-87

NEW ORLEANS (AP) — Kobe Bryant scored 29 points, making him the fifth player in NBA history to score 30,000, and the Los Angeles Lakers snapped a two-game skid with a 103-87 victory over the New Orleans Hornets on Wednesday night.

Bryant entered the game needing only 13 points to eclipse the scoring milestone and did so with a short jumper late in the first half that was perhaps the least spectacular of his baskets, which included the usual array of soaring dunks, demoralizing transition 3-pointers and turnaround, off-balance jumpers.

Dwight Howard added 18 points and five blocked shots for the Lakers, who trailed 48-47 at halftime but seized control with a 13-0 run to open the third quarter, and the lead grew as large as 20 in the fourth.

Ryan Anderson scored 31, hitting 5 of 8 3-pointers for the Hornets, who were playing their ninth straight game without top overall draft choice Anthony Davis. Greivis Vasquez added 16 points, while Robin Lopez scored 15 points and blocked five shots.

Antawn Jamison scored 15 and Metta World Peace 11, and Chris Duhon had 10 assists for Los Angeles, which is playing without Steve Nash and Pau Gasol and won for only the second time on the road this season. The Hornets fell to 3-7 at home and lost for the 10th time in 12 games overall.

The Hornets led from early in the first quarter until halftime, going up by as many as eight points when Al-Farouq Aminu slammed down an alley-oop lob from Vasquez, energizing the largest crowd of the season at the New Orleans Arena.

Bryant helped the Lakers trim their deficit after that, hitting five free throws and his milestone on 3-foot jumper in the last 2:15 of the second quarter.

Jamison opened the third-quarter onslaught with 3, Howard followed with a fast-break layup and Bryant had two straight fast-break dunks, one of which he created himself with a steal.

Howard finished the surge with a layup.

Anderson's shooting helped the Hornets pull to 70-62 late in the third period, but Bryant hit an 18-footer and Jodie Meeks added one of his three 3-pointers to give Los Angeles a 13-point lead heading into the final period. Meeks and Darius Morris then added 3s early in the period and New Orleans could not recover.

Notes: NBA Commissioner David Stern attended the game and said he was happy to be in attendance for Bryant's milestone moment, even if the scheduling was pure coincidence. Stern was making a regularly scheduled visit with first-year Hornets owner Tom Benson, who is also the owner of the NFL's Saints, to see how Benson's plans for the NBA franchise were taking shape. Stern visited Saints headquarters, where new construction has begun on additions that will also accommodate Hornets offices and practice courts. Stern said he wanted to shake hands with Bryant after the game. "As a talent, a competitor, I think that he is up there on the pedestal with Michael Jordan. He is one of the greatest." ... Stern also discussed the possibility of a team name change, something Benson has said he wants since buying the club last spring. Stern says the club has not yet applied for a name change but that the league would likely accept whatever name the Hornets want and expedite the transition.

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Obama leads heads of state atop Forbes 2012 power list

NEW YORK (Reuters) – When it comes to power, politics trumps business, according to a new Forbes ranking on Wednesday that found heads of state occupying six of the top 10 spots among the world’s most powerful people, led by President Barack Obama.

The annual list selected what Forbes said were the world’s 71 most-powerful people from among the roughly 7.1 billion global populace, based on factors ranging from wealth to global influence.

Obama was joined in the top 10 by German Chancellor Angela Merkel, Russian President Vladimir Putin, King Abdullah bin Abdulaziz al Saud of Saudi Arabia and British Prime Minister David Cameron.

The list’s highest-ranked businessman was Microsoft co-founder Bill Gates at No. 4. U.S. Federal Reserve Chairman Ben Bernanke and European Central Bank President Mario Draghi, both public officials, also made the top 10.

“This year’s list reflects the changing of the guard in the world’s two most powerful countries: the United States and China,” Michael Noer, Forbes‘ executive editor, told Reuters in an email.

Noer noted that China’s President Hu Jintao, last year’s third most-powerful person, fell off the list as he is leaving power, and his successor, Xi Jinping, ranked ninth instead.

Both U.S. Treasury Secretary Timothy Geithner and Secretary of State Hillary Clinton, who have stated they will not be serving in Obama’s second term, were not in this year’s rankings.

While elected and appointed officials and business people made up the vast majority of Forbes’ most powerful, Pope Benedict XVI placed fifth in the rankings.

Among the oddities was Joaquin Guzman Loera at No. 63.

Loera, far from a household name, is a billionaire nicknamed “El Chapo” who as head of Mexico’s Sinaloa cartel is the world’s most powerful drug trafficker, according to Forbes.

Age was also not a barrier, with two of the youngest and oldest of this year’s most powerful — 28-year-old Facebook CEO Mark Zuckerberg and 81-year-old News Corp CEO Rupert Murdoch — back-to-back at numbers 25 and 26, respectively.

Forbes noted that Zuckerberg fell out of last year’s top 10 after Facebook’s IPO disappointed. A gainer, meanwhile, was Brazilian President Dilma Rousseff, who moved up four spots to No. 18 despite being only halfway into her first term of office.

To create the rankings, which Forbes readily concedes bore a measure of subjectivity, editors graded candidates on four criteria for power and averaged the four grades:

– Power over many people

– Control over financial and other valuable resources

– Power in multiple spheres or arenas

– Active use of power

Some measures, such as power over many people, favored leaders such as the Pope, while the world’s richest man — Mexican telecom magnate Carlos Slim Hula, worth a reported $ 72 billion — placed 11th on the strength of his wealth.

Others, such as New York’s billionaire Mayor Michael Bloomberg, scored high in all areas, placing him at No. 16.

Noer said that Elon Musk, one of the co-founders of Paypal and Tesla Motors, was “one of the more interesting newcomers” on the list due to his SpaceX company, a private space exploration venture.

“With NASA retiring the space shuttle fleet, private companies like SpaceX have been awarded huge contracts to do things like resupply the International Space Station. The commercialization of space is just beginning, but we expect it to be big business,” Noer said.

Former President Bill Clinton placed 50th, with editors noting that by hitting the campaign trail for Obama, Clinton “cemented his status as a kingmaker”, along with his nonpartisan Global Initiative raising more than $ 71 billion in commitments to fund charitable action worldwide.

Other high-ranking heads of state included French President Francois Hollande at No. 14, Indian Prime Minister Manmohan Singh at No. 19 and Iran’s Grand Ayatollah Ali Hoseini-Khamenei at No. 21.

Among businessmen in the top 20 were Berkshire Hathaway CEO Warren Buffett at No. 15, Wal-Mart CEO Michael Duke at No. 17 and Google co-founders Larry Page and Sergey Brin at No. 20.

The entire list can be found at www.forbes.com/power as well as the December 24 issue of the magazine.

(Reporting by Chris Michaud, Editing by Piya Sinha-Roy and Andrew Hay)

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Study could spur wider use of prenatal gene tests

A new study sets the stage for wider use of gene testing in early pregnancy. Scanning the genes of a fetus reveals far more about potential health risks than current prenatal testing does, say researchers who compared both methods in thousands of pregnancies nationwide.

A surprisingly high number — 6 percent — of certain fetuses declared normal by conventional testing were found to have genetic abnormalities by gene scans, the study found. The gene flaws can cause anything from minor defects such as a club foot to more serious ones such as mental retardation, heart problems and fatal diseases.

"This isn't done just so people can terminate pregnancies," because many choose to continue them even if a problem is found, said Dr. Ronald Wapner, reproductive genetics chief at Columbia University Medical Center in New York. "We're better able to give lots and lots of women more information about what's causing the problem and what the prognosis is and what special care their child might need."

He led the federally funded study, published in Thursday's New England Journal of Medicine.

A second study in the journal found that gene testing could reveal the cause of most stillbirths, many of which remain a mystery now. That gives key information to couples agonizing over whether to try again.

The prenatal study of 4,400 women has long been awaited in the field, and could make gene testing a standard of care in cases where initial screening with an ultrasound exam suggests a structural defect in how the baby is developing, said Dr. Susan Klugman, director of reproductive genetics at New York's Montefiore Medical Center, which enrolled 300 women into the study.

"We can never guarantee the perfect baby but if they want everything done, this is a test that can tell a lot more," she said.

Many pregnant women are offered screening with an ultrasound exam or a blood test that can flag some common abnormalities such as Down syndrome, but these are not conclusive.

The next step is diagnostic testing on cells from the fetus obtained through amniocentesis, which is like a needle biopsy through the belly, or chorionic villus sampling, which snips a bit of the placenta. Doctors look at the sample under a microscope for breaks or extra copies of chromosomes that cause a dozen or so abnormalities.

The new study compared this eyeball method to scanning with gene chips that can spot hundreds of abnormalities and far smaller defects than what can be seen with a microscope. This costs $1,200 to $1,800 versus $600 to $1,000 for the visual exam.

In the study, both methods were used on fetal samples from 4,400 women around the country. Half of the moms were at higher risk because they were over 35. One-fifth had screening tests suggesting Down syndrome. One-fourth had ultrasounds suggesting structural abnormalities. Others sought screening for other reasons.

"Some did it for anxiety — they just wanted more information about their child," Wapner said.

Of women whose ultrasounds showed a possible structural defect but whose fetuses were called normal by the visual chromosome exam, gene testing found problems in 6 percent — one out of 17.

"That's a lot. That's huge," Klugman said.

Gene tests also found abnormalities in nearly 2 percent of cases where the mom was older or ultrasounds suggested a problem other than a structural defect.

Dr. Lorraine Dugoff, a University of Pennsylvania high-risk pregnancy specialist, wrote in an editorial in the journal that gene testing should become the standard of care when a structural problem is suggested by ultrasound. But its value may be incremental in other cases and offset by the 1.5 percent of cases where a gene abnormality of unknown significance is found.

In those cases, "a lot of couples might not be happy that they ordered that test" because it can't give a clear answer, she said.

Ana Zeletz, a former pediatric nurse from Hoboken, N.J., had one of those results during the study. An ultrasound suggested possible Down syndrome; gene testing ruled that out but showed an abnormality that could indicate kidney problems — or nothing.

"They give you this list of all the things that could possibly be wrong," Zeletz said. Her daughter, Jillian, now 2, had some urinary and kidney abnormalities that seem to have resolved, and has low muscle tone that caused her to start walking later than usual.

"I am very glad about it," she said of the testing, because she knows to watch her daughter for possible complications like gout. Without the testing, "we wouldn't know anything, we wouldn't know to watch for things that might come up," she said.

The other study involved 532 stillbirths — deaths of a fetus in the womb before delivery. Gene testing revealed the cause in 87 percent of cases versus 70 percent of cases analyzed by the visual chromosome inspection method. It also gave more information on specific genetic abnormalities that couples could use to estimate the odds that future pregnancies would bring those risks.

The study was led by Dr. Uma Reddy of the National Institute of Child Health and Human Development.

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Online:

Medical journal: http://www.nejm.org

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Stars out in London for 'Les Mis' premiere

LONDON (AP) — Hollywood stars Anne Hathaway and Hugh Jackman have braved the London cold to walk the red carpet for the world premiere of "Les Miserables."

Hathaway said at the premiere Wednesday that playing the role of Fantine in the film adaptation of "Les Mis" was a dream job she would have done anything to land, describing the gig as "the sort of job you should give your paycheck back" for.

The 30-year-old actress lost 25 pounds (11.3 kilograms) and cut her hair to play the role of a struggling, sickly mother forced into prostitution in 1800s Paris in the screen adaptation of Victor Hugo's classic.

Joined by Jackman and other costars Russell Crowe and Amanda Seyfried, Hathaway signed autographs and met fans in central London at the event.

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