EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Justin Bieber wins 3 AMAs, including top honor

America proved its Bieber Fever was strong: The teen singer dominated the American Music Awards on Sunday night.

Bieber's wins included the show's top award, artist of the year.

The singer's mom joined him onstage as he collected the top award.

He looked to his mom: "I wanted to thank you for always believing in me."

He said it's "hard growing up with everyone watching me" and asked that people continue to believe in him.

The 18-year-old also won favorite pop/rock album for "Believe" and male artist.

He performed two songs at the award show, one stripped and another upbeat with Nicki Minaj. As Bieber won his second award, he was kissed on the neck by Jenny McCarthy, who presented the award.

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Investors rush in to rent out foreclosures









The foreclosed home on Kenmore Street in Aurora was an outdated, unkempt eyesore until crews arrived this fall, performing thousands of dollars of work to make it attractive and modern, inside and out.


But it wasn't until workers walked across the street to ask for some water that neighbors Mario Cervantes and Oralia Balderas-Cervantes learned that a corporation, not a consumer, had bought the house, intending to turn it into a rental property. Despite being landlords themselves, the couple aren't sure they like the idea.


"If it's going to be a company that is watching out for the community, yes," Cervantes said. "If it's going to be a company that is watching out for themselves, no."





Added Balderas-Cervantes: "I'd rather see a homeowner. A lot of renters don't care. It's like renting a car versus buying a car. It's different."


Similar scenarios and concerns are unfolding across Chicago and in other markets hard-hit by the housing crisis. Well-capitalized, out-of-town private equity funds are scouring neighborhoods, paying cash for distressed single-family homes and renting them out. The opportunities are plentiful, enabling investment groups to profit from low home prices, rising rents and an increase in the number of potential renters.


The transactions are returning vacant properties to active use. But they also are stoking fears among neighbors and municipalities about the long-term effect of large, private investors — including many that are operating under the radar — in their communities.


"This scares the hell out of me," said Ed Jacob, executive director of Neighborhood Housing Services of Chicago Inc. "In this rush to say this is a new asset class, are we creating the next community development problem?


"You talk to them and it's all about neighborhood recovery. They all have the narrative down."


In April, housing research firm CoreLogic named the Chicago area one of the better housing markets for institutional investor funds. It cited the area's large number of foreclosures, which will increase the number of vacant homes, and the estimated rental income relative to the low cost of acquisition.


The general strategy of the companies is the same: buy low, make the necessary upgrades, fill them with tenants and then sell the homes in three to seven years. With companies and analysts anticipating projected returns of at least 8 percent, there also is talk of creating publicly traded real estate investment trusts.


"What this reminds me of is the dot-com boom," said Rick Sharga, executive vice president of Carrington Mortgage Holdings LLC, a California firm whose asset management arm is actively looking in the Chicago market. "That's what this feels like. Every investor in America wants to buy foreclosures and turn them into rentals."


Two statistics increasing that appetite are the homeownership rate and rental rates. Foreclosures, tight lending conditions and wary consumers have pushed down the nation's homeownership rate to 65.5 percent at the end of September, according to census data. Meanwhile, the percentage of vacant rental units has been on a steady decline since 2010 as more people opt for leases rather than mortgages.


Tighter inventories are pushing up rents. As of October, annualized rents in Chicago were up 7.7 percent, more than the national increase of 5.1 percent, online real estate site Trulia found.


But investors aren't flocking to all neighborhoods equally. Most want homes in desirable neighborhoods with strong area employment. They also look at the strength of local rules protecting landlords in disputes with tenants.


After vetting the tenant and securing a lease, property managers say they routinely drive by the homes and sometimes schedule inside inspections to protect their investment.


Weighing risks, rewards


It remains to be seen whether their expectations will be met. One problem with the business model is there's no performance track record to speak of. And as housing prices slowly recover, acquisition costs also will increase and cut into returns.


There also isn't any history on property management firms tasked with overseeing so many scattered-site rental properties. Any well-publicized mistakes involving poorly maintained properties or wronged tenants could taint investors' reputations.


That's one reason why big-name players are likely to avoid buying in neighborhoods where they fear a greater chance of eviction proceedings occurring.


"You make one mistake in those properties and you'll be toast," Sharga said.





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Notre Dame pounds Wake Forest









SOUTH BEND, Ind. — Out he came with a double-tap to his chest and a finger pointed to the sky. Then Manti Te'o ran on to the field one last time, spinning around with his arms open to a Notre Dame Stadium crowd madly waving green and white leis for him and him alone.

As he approached midfield, the Irish linebacker ripped his helmet off before a bear hug from his father, who told his son he loved him, how proud of him he was. Everyone cried. And then Te'o was alone, off to a corner of the field, to blow kisses to the student section before going to work.

After No. 3 Notre Dame mushroom-clouded its way to a 38-0 obliteration of Wake Forest and its first 11-0 start in 23 years, Te'o wound up chin-deep in leis, made of everything from flowers to beef jerky packets. He received a standing ovation, he heard his name chanted, and his skin tingled.

"Just magic," Te'o said. "There are no words to describe this place and how I felt at that time. Just joy. Pure joy."

To think it was only the beginning of the end. The exhilarating run arrives in southern California next weekend, one game against punch-drunk rival USC, one game for a possible chance at a national title and a gilded page in the densest college football history tome there is.

Only, in essence, the most important game they ever have played.

"We're going to be more focused than ever," said receiver John Goodman, who had a 50-yard touchdown catch. "The program is at an all-time high. It's something we want to keep going. We won't let USC get in our way. We just know we have one more, and we're good to go for a national championship, hopefully."

As for this Saturday, the celebration raged on after Senior Day festivities ended. Quarterback Everett Golson's 20-for-30, 346-yard, three-touchdown day spurred 584 yards of offense and the defense's first shutout since the 2009 opener turned Wake Forest (5-6) into dust.

Four plays in, tailback Cierre Wood was in the end zone after a 68-yard run. Then came Golson's three scoring tosses: A 2-yarder to Tyler Eifert, the bomb to Goodman and a 34-yard floater to TJ Jones.

The Irish were up 31 at halftime. Notre Dame won five previous home games by 23 points, total. Wake Forest was rendered indistinguishable from the marshmallows squished on the sideline after the students hurled them from the stands.

"I thought everything came together," Golson said. "My head is down, my foot's on the gas. I'm never going to look up and lose focus."

So here comes USC, hated USC, the Trojans either swashbuckling in pursuit of ruining their rivals' dreams … or devastated as a season of disappointment grinds to a close.

"Our guys know what's at stake now," Irish coach Brian Kelly said. "This is about an undefeated season. They cannot do anything else but beat USC. The rest is up to other people to decide."

It all comes to an end for the Irish, one way or another. Early in the fourth quarter Saturday, at a timeout that became a send-off, Te'o followed seniors Kapron Lewis-Moore and Zeke Motta to the sideline. Te'o pounded his chest, then screamed and punched the night air all the way there.

One of the best nights of their lives, and here comes the biggest.

bchamilton@tribune.com

Twitter @ChiTribHamilton



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Exclusive: Facebook offering e-retailers sales tracking tool

SAN FRANCISCO (Reuters) - Facebook Inc wants more credit for making online cash registers ring.


Facebook will begin rolling out on Friday a new tool which will allow online retailers to track purchases by members of the social network who have viewed their ads.


The tool is the latest of the new advertising features Facebook is offering to convince marketers that steering advertising dollars to the company will deliver a payoff.


Facebook, with roughly 1 billion users, has faced a tough reception on Wall Street amid concerns about its slowing revenue growth.


"Measuring ad effectiveness and outcomes is absolutely crucial to all types of businesses and marketers," said David Baser, a product manager for Facebook's ads business who said the "conversion measurement" tool has been a top customer request for a long time.


The sales information that advertisers receive is anonymous, said Baser. "You would see the number of people who bought shoes," he said, using the example of an online shoe retailer. But marketers would not be able to get information that could identify the people, he added.


The conversion tool is specifically designed for so-called direct response marketers, such as online retailers and travel websites that advertise with the goal of drumming up immediate sales rather than for longer-term brand-building.


Such advertisers have long flocked to Google Inc's Web search engine, which can deliver ads to consumers at the exact moment they're looking for information on a particular product.


But some analysts say there is room for Facebook to make inroads if it can demonstrate results.


"The path to purchase" is not as direct on Facebook as it is on Google's search engine, said Debra Aho Williamson, an analyst with research firm eMarketer. But she said that providing information about customer sales conversion should help Facebook make a stronger case to online retailers.


"It lets marketers track the impact of a Facebook ad hours or days or even a week beyond when someone might have viewed the ad," said Williamson. "That allows marketers to understand the impact of the Facebook ad on the ultimate purchase."


Marketers will also have the option to aim their ads at segments of Facebook's audience with similar attributes to consumers that have responded well to a particular ad in the past, Baser said.


Online retailer Fab.com, which has tested Facebook's new service, was able to reduce its cost per new customer acquisition by 39 percent when it served ads to consumers deemed most likely to convert, Facebook said. Facebook defines a conversion as anything from a completed sale, to a consumer taking another desired action on a website, such as registering for a newsletter.


NEW OPPORTUNITIES


Shares of Facebook, which were priced at $38 a share in its May initial public offering, closed Thursday's regular session at $22.17.


In recent months, Facebook has introduced a variety of new advertising capabilities and moved to broaden its appeal to various groups of advertisers.


Chief Operating Officer Sheryl Sandberg said in October that Facebook saw multi-billion revenue opportunities in each of four groups of advertisers: brand marketers, local businesses, app developers and direct response marketers.


Facebook does not disclose how much of its ad revenue, which totaled $1.09 billion in the third quarter, comes from each type of advertiser. Pivotal Research Group analyst Brian Wieser estimates that brand marketers and local businesses account for the bulk of Facebook's current advertising revenue.


Earlier this year, Facebook introduced a similar conversion measurement service for big brand advertisers, such as auto manufacturers, partnering with data mining firm Datalogix to help connect the dots between consumer spending at brick-and-mortar and Facebook ads.


And Facebook has rolled out new marketing tools for local businesses such as restaurants and coffee shops, including a revamped online coupon service and simplified advertising capabilities known as promoted posts.


The new conversion measurement tool is launching in testing mode, but will be fully available by the end of the month, Facebook said.


(Reporting By Alexei Oreskovic; editing by Carol Bishopric)


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No. 6 Buckeyes beat Wisconsin in OT, 21-14

MADISON, Wis. (AP) — Ohio State clinched one title, and kept its slim hopes for another alive.

The sixth-ranked Buckeyes won the Leaders Division crown outright Saturday, beating Wisconsin 21-14 on Carlos Hyde's 2-yard scoring run in overtime. Buckeyes safety Christian Bryant batted down Curt Phillips' pass on fourth down to preserve the win.

Ohio State (11-0, 7-0 Big Ten) is ineligible for the postseason as part of its punishment for NCAA violations under former coach Jim Tressel. The best the Buckeyes can hope for is to finish the regular-season unbeaten, then have the teams above them all lose at least once to give them a shot at playing spoiler for The Associated Press title.

"We have a saying, 'A team that refuses to be beat won't be beat,'" Ohio State coach Urban Meyer said. "Somehow, someway."

Wisconsin, meanwhile, blew its chance to show it deserves its spot in next month's Big Ten title game. The Badgers (7-4, 4-3) are third in the Leaders Division, but they'll be playing for a trip to the Rose Bowl because neither the Buckeyes nor Penn State are eligible for the postseason. No one else in the division will even finish with a winning record.

"I'm sure winning in Indy and going to the Rose Bowl and winning there would erase all the losses we've had," Montee Ball said. "Because that's our goal."

At least the Wisconsin fans got to see Ball get the major college record for career touchdowns in his final home game. Or, part of the record anyway. Ball scored his 78th TD in the second quarter, tying the mark set by Travis Prentice of Miami (Ohio) in 1999.

But he fumbled what would have been the record-breaker with 2:46 left in regulation. Ball held the ball in front of him as he leaped over the pile on the goal line, and Buckeyes linebacker Ryan Shazier met him with both fists and punched the ball loose.

"That's a dumb decision on my part," Ball said. "But I just felt like I needed to get the ball in the end zone."

And the Buckeyes felt just as strongly that they needed to keep him out.

"We knew that he needed two to break the record," Shazier said. "We were not going to allow him to break it on us."

Ball finished with 191 yards on a career-high 39 carries.

The Ohio State-Wisconsin rivalry hasn't reached the heights of "The Game" between the Buckeyes and Michigan. But it is not exactly warm and fuzzy, either, especially not after the previous two games.

Two years ago, Wisconsin ended Ohio State's hopes of a making a run at the national title, handing the then-No. 1 Buckeyes their first loss at Camp Randall. (Ohio State's 2010 season was later erased by the NCAA sanctions.) Last year it was the Buckeyes stunning the Badgers, with Braxton Miller dancing around like a jitterbug before launching a 40-yard, game-winning heave with 20 seconds left.

Though there wasn't any obvious chippiness Saturday, the brutal physicality of the game left no doubt the teams have begun to use each other as a measure. Wisconsin's defense was downright nasty, limiting the high-powered Buckeyes to a mere 236 yards of offense, more than 200 yards below their average. The Buckeyes crossed the midfield only once after halftime, and the Badgers largely kept the dynamic Miller in check.

But Miller made plays when he needed to, and Hyde continued to impress.

"We're certainly not a finished product on offense, and it showed," Meyer said. "But to come down in that overtime. I think we need to give (Hyde) the ball a little bit more."

After Ball's goal-line fumble, the Badger defense came up with one more big stop, a quick three-and-out that ensured the offense would have good field position. It was the first two-minute drill for Curt Phillips, the third-string quarterback who was making his second start, and he got off to a rough start, sacked on the first play.

He settled down from there, though, converting a fourth down with a 14-yard pass to Jared Abbrederis and finding him for another long gain to set up Jacob Pedersen's 5-yard scoring catch that tied the game with eight seconds left.

"Everybody kept the faith. We drove right down and scored," Phillips said. "I was very confident going into the overtime."

But overtime was all Buckeyes. Hyde ripped off a run of 11 yards on the first play and, two plays later, strolled virtually untouched into the end zone for the go-ahead score.

He also had a 15-yard scoring run in the second quarter, and finished with 87 yards on 15 carries. Miller was 10 of 18 passing for 97 yards, and had another 48 yards rushing. He also was sacked three times for a loss of 27 yards.

"We just wanted to pound the ball and give the ball to Carlos and let the O-line block for Carlos because we knew it was over," said Corey "Philly" Brown, who returned a punt 68 yards for a score. "That O-line is something else. We don't think there is any D-line that can stop them when you have a back like Carlos running the ball."

The Badgers have a good back of their own, but the Buckeyes knew the game was theirs.

"We knew that if our offense scored, we were going to win," cornerback Bradley Roby said. "The touchdown they scored (at the end of regulation) gave us motivation to win it in overtime."

Ball gained 6 yards on Wisconsin's opening play, but that was all the Badgers would get. Phillips threw an incompletion, Ball was hauled down for a loss and Bryant batted down a Phillips pass intended for Pedersen to end the game.

"We still have another game to go and obviously it's the biggest one," Brown said. "It's our last, so we're going to make it count."

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Lady Gaga tweets some racy images before concert

BUENOS AIRES, Argentina (AP) — Lady Gaga's tweets were getting a lot of attention ahead of her Buenos Aires concert Friday night.

The Grammy-winning entertainer has more than 30 million followers on Twitter and that's where she shared a link this week to a short video showing her doing a striptease and fooling around in a bathtub with two other women.

She told her followers that it's a "surprise for you, almost ready for you to TASTE."

Then, in between concerts in Brazil and Argentina, she posted a picture Thursday on her Twitter page showing her wallowing in her underwear and impossibly high heels on top of the remains of what appears to be a strawberry shortcake.

"The real CAKE isn't HAVING what you want, it's DOING what you want," she tweeted.

Lady Gaga wore decidedly unglamorous baggy jeans and a blouse outside her Buenos Aires hotel Thursday as three burly bodyguards kept her fans at bay. Another pre-concert media event where she was supposed to be given "guest of honor" status by the city government Friday afternoon was cancelled.

After Argentina, she is scheduled to perform in Santiago, Chile; Lima, Peru; and Asuncion, Paraguay, before taking her "Born This Way Ball" tour to Africa, Europe and North America.

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Chocolatier finds sweet spot in Belize








Katrina Markoff, the founder of high-end Chicago chocolatier Vosges Haut-Chocolat, is nearing completion on two high-profile projects: a winery-style chocolate facility in Logan Square and an education center at a cacao plantation and eco-lodge in Belize.


Markoff isn't ready to talk about the Logan Square project, her spokeswoman said. But in an interview last week, she said she hopes the Belcampo farm in Belize will become the source of a majority of Vosges' cacao once its plants mature.


The project means Markoff will soon play a role in every aspect of production from seed selection through packaging without having to assume the financial risk of owning a tropical plantation.






Belcampo Group CEO Anya Fernald said the education center that Markoff helped design will open in mid-December, and Markoff will teach her first "master class" on cacao to guests at the 12-room lodge April 23-27. In exchange for her time and expertise, Markoff will receive a better price on the beans.


"I've always wanted to be involved through the full vertical, from actually growing the varietals of cacao I want, and being particular about how they're grown and harvested and fermented and dried," she said.


Once the farm reaches full yield in about five years, Fernald estimated it will produce 250,000 pounds of cacao annually. Already, with only 60 acres planted so far — all under a rain forest canopy — Fernald said Belcampo is already Belize's largest cacao plantation.


"The integrity of that project is really, really unique and special," Markoff said. "Typically when people buy beans to make chocolate, they just buy whatever is available in the commodity market. There's not a lot of control over how it's grafted, where it's planted, how it's nurtured, who's taking care of it. You just don't get that kind of control."


Bluhm continues gambling push


Chicago real estate and gambling executive Neil Bluhm is entering the race to build one of four planned casinos in Massachusetts and has launched an online gaming division in Chicago, said Greg Carlin, chief executive of Bluhm's Rush Street Gaming.


Earlier this year Rush Street hired Richard Schwartz from Waukegan-based WMS Industries and appointed him president of Rush Street Interactive, its new online gaming division.


"We think (Internet gaming) is going to be eventually legalized throughout the country, or in jurisdictions that have bricks-and-mortar casinos," Carlin said. "Illinois is actually a leader in selling lottery tickets online and could be a leader in Internet gaming as well if they get ahead of the curve and pass legislation before some of the other states."


Nevada and Delaware have legalized some forms of Internet gambling.


In recent years, Bluhm has built three casinos: Rivers Casino in Des Plaines, one in Pittsburgh and another in Philadelphia. In October, Bluhm sold his first U.S. casino, Riverwalk Casino and Hotel, in Vicksburg, Miss., for $141 million in cash to Churchill Downs Inc. (Bluhm held a 70 percent stake in Riverwalk.)


Churchill Downs, a horse racing and wagering company, also owns Arlington Park in Arlington Heights. Its largest shareholder is Duchossois Group, founded by Arlington Park Chairman Richard "Dick" Duchossois.


Duchossois has been trying to persuade the Illinois Legislature to approve slots at racetracks, which, if successful, would make Arlington Park a competitor of Bluhm's Des Plaines casino.


As for the Massachusetts casino, the gambling commission there will weigh applications for casino licenses well into 2013.


Alvarez joins Culloton


Public relations firm Culloton Strategies has hired Michael Alvarez, a commissioner of the Metropolitan Water Reclamation District of Greater Chicago, as senior vice president for public affairs.


As the Sun-Times reported in January, Alvarez, 32, has worked for Barack Obama, Rod Blagojevich and Richard M. Daley — while he has close ties to Ald. Richard Mell, Blagojevich's father-in-law.


In addition to his $70,000 annual salary at the water district, Alvarez has a $60,000-a-year public relations contract with the Illinois Sports Facilities Authority and a "fast-growing" lobbying practice, the Sun-Times reported.






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Former Bears coach Mike Ditka suffers 'very minor stroke'









Former Bears coach and Hall of Fame tight end Mike Ditka was hospitalized Friday after suffering what he said doctors told him was a "very minor stroke."

Contacted Friday evening, Ditka said, "I feel good right now and it's not a big deal."

Ditka was at a suburban country club playing cards Friday when he noticed his hands "weren't working quite right," and then he had a problem speaking.

Ditka, 73, has not had any major health problems in recent years. But in 1988 when he was coaching the Bears he suffered a heart attack.

These days, Ditka spends his time doing broadcast work for ESPN, tending to his restaurant Ditka's on East Chestnut in the Tremont Hotel, making appearances and golfing.

An ESPN producer tweeted that Ditka will not fulfill his ESPN duties from Bristol, Conn., this weekend.

After he suffered his heart attack at 49, he was back in the office eight days later and back on the sidelines in 11 days against doctor's orders.

At the time, Ditka said he was "embarrassed" by the heart attack, and he reflected on his mortality when he returned to Halas Hall.

"I don't know what I experienced," he said at the time. "I think I almost experienced embarrassment. It kind of was embarrassing that it happened to me. I mean, how could this ever happen to me? That's the way I felt in the beginning, and then it didn't matter. I mean it was so bad at a certain point that I knew that we're just mortals. I mean, we're here for a while and then we're gone. It can happen to anybody at any time. It was a very humbling feeling after that, believe me."

The Bears made Ditka the fifth overall pick in the 1961 draft out of Pittsburgh. He was rookie of the year and went to five straight Pro Bowls for the Bears. As a pass catching tight end, he helped redefine the position.

Ditka eventually ran afoul of owner-coach George Halas and was traded to the Eagles in 1967. He finished up his playing career with the Cowboys.

In 1982, Halas hired Ditka to coach his team. Ditka was coach of the year in 1985, when the Bears won the Super Bowl, and in 1988. After going 5-11 in 1992, Ditka was fired.

He coached the Saints for three seasons, retiring with a record of 121-95, before settling into his broadcasting career.
Ditka is one of only two men, Tom Flores being the other, to win a Super Bowl as a player, assistant coach and head coach.

dpompei@tribune.com

Twitter@dan pompei



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